Synthetic Biology and Tissue Engineering

Cancer systems biology

Cancer systems biology encompasses the application of systems biology approaches to cancer research, in order to study the disease as a complex adaptive system with emerging properties at multiple biological scales.

Cancer systems biology therefore adopts a holistic view of cancer aimed at integrating its many biological scales, including genetics, signaling networks, epigenetics, cellular behavior, histology, (pre)clinical manifestations and epidemiology. The systems biology approach relies heavily on the successes of decades of reductionism, which has clarified the component parts and mechanistic principles of living organisms, as well as their key alterations in cancer, especially at the genetic/genomic scale, to deep detail.