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4th International Conference on Systems and Synthetic Biology, will be organized around the theme “Design and construct new biological parts for novel functions”

Systems and Synthetic Biology 2018 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Systems and Synthetic Biology 2018

Submit your abstract to any of the mentioned tracks.

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Systems and Synthetic Biology is a relatively new field in biomedical research. It focuses on engineering new or modified signaling proteins to create desired signaling pathways in the cell. Every living cell is an extremely complex machine expressing thousands of different proteins. Due to superb regulation, many cells, such as photoreceptors and other neurons in vertebrates, can live for decades. Cells can also self-reproduce by division, where both daughter cells are perfectly viable. Natural selection (the “blind watchmaker”, to use Dawkins’ expression) spent hundreds of millions of year to achieve this perfection. Due to elucidation of the intricacies of cellular regulatory mechanisms we can now play evolution on our time scale: re-design proteins and signaling pathways to achieve our ends.

  • Track 1-1Systems Biology
  • Track 1-2Gene Signaling
  • Track 1-3Genome Design
  • Track 1-4 Bioprocessing Engineering
  • Track 1-5Cell Growth and Cell Culture

The field of molecular biology covers with biology and chemistry and specifically, genetics and biochemistry. A key territory of molecular biology concerns seeing how different cell systems connect as far as the way DNA, RNA and protein synthesis function. Molecular biology takes a gander at the molecular mechanisms behind procedures, for example, replication, transcription, translation and cell function. The Scientist must decide how biological traits are conveyed starting with one generation to another. Molecular biologists also analyse. They utilize this data to help with the determination and treatment of infections found in humans, plants and animals.

  • Track 2-1Molecular systems biology
  • Track 2-2Plant systems biology
  • Track 2-3Bioinformatics and systems biology
  • Track 2-4Cell and systems biology
  • Track 2-5Cell signaling
  • Track 2-6Sequence profiling tools

CRISPR-Cas9 is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA Sequence.It is currently the simplest, most versatile and precise method of genetic manipulation and is therefore causing a buzz in the science world.

The CRISPR-Cas9 system consists of two key molecules that introduce a change (mutation) into the DNA. These are an enzyme Called Cas9. This acts as a pair of ‘molecular scissors’ that can cut the two strands of DNA and a piece of RNA Called guide RNA (gRNA) which binds to DNA. The Cas9 follows the guide RNA to the same location in the DNA sequence and makes a cut across both strands of the DNA. At this stage the cell recognises that the DNA is damaged and tries to repair it.

  • Track 3-1CRISPR-Cas9 Technology Information
  • Track 3-2Designer TALEN Technology Information
  • Track 3-3High-throughput functional genomics using CRISPR–Cas9
  • Track 3-4Improving genome editing with drugs
  • Track 3-5CRISPR mRNA and protein

As name "Integrative Biology" reflects conviction that the investigation of biological systems is best drawn nearer by fusing numerous points of view. We unite assorted qualities of controls that supplement each other to disentangle the complexity of biology. The idea incorporates anatomy, physiology, cell and stem cell biology, molecular biology, developmental biology, biochemistry and biophysics. We work with animals, plants and microorganisms and our exploration traverses the levels of the organic chain of command from molecules to ecosystems. Our expansive scope of mastery incorporates: geneticists, paleontologists, physiologists, behaviorists, systematists, morphologists, microbiologists, bioinformatician, evolutionary biologists, ecologists, biophysicists and biotechnologists.

  • Track 4-1Computational Bio modeling
  • Track 4-2Computational Genomics
  • Track 4-3Computational Neuroscience
  • Track 4-4Computational Pharmacology
  • Track 4-5Computational Evolutionary biology
  • Track 4-6Cancer Computational Biology

Metabolomics is the experimental investigation of concoction procedures including metabolites. In particular, metabolomics is the deliberate investigation of the exceptional substance fingerprints that particular cell forms desert, the investigation of their little molecules metabolite profiles. The metabolome speaks to the accumulation of all metabolites in a biological cell, tissue, organ or living being, which are the end products of cell processes. mRNA quality expression data and proteomic examinations uncover the set of gene products being created in the cell, data that speaks to one part of cell function. On the other hand, metabolic profiling can give an immediate depiction of the physiology of that cell. One of the difficulties of system biology and functional genomics is to integrate proteomic, transcriptomic, and metabolomic data to give a superior comprehension of cell biology.

  • Track 5-1Cell immune system
  • Track 5-2Human cell system
  • Track 5-3Human primary cells
  • Track 5-4Adult stem cells
  • Track 5-5Primary cancer cell culture
  • Track 5-6Cell & Gene therapy
  • Track 5-7Stem Cell Technologies

Synthetic biology has pioneered transformative approaches that are affecting how scientists tackle key questions in mammalian cell biology. Synthetic biology techniques have wide-ranging applicability and commonly make use of genetic devices, or collections of genetic elements encoding particular functions, for probing key cellular mechanisms. Early success focused on engineered transcription-based regulatory systems primarily in bacteria. More recently, new endeavors have shifted to mammalian gene regulatory processes to allow flexible, precise, and comprehensive control over gene expression and cellular development. Novel and more complex genetic devices have been used to probe cellular mechanisms, including alternative splicing, RNAi, and epigenetics.

  • Track 6-1Production of Natural products from synthetic biology
  • Track 6-2Production of Bio-Fuels, Chemicals and Pharmaceuticals
  • Track 6-3Industry Uses of Synthetic Biology
  • Track 6-4Industrial Production of Green Chemicals
  • Track 6-5Therapeutic Cells

Synthetic genomics is an early field of engineered science that uses parts of hereditary alteration on prior life frames with the plan of delivering some item or wanted conduct with respect to the living thing so made.Synthetic genomics joins strategies for the fake amalgamation of DNA with computational methods to plan it. These strategies permit researchers and specialists to build hereditary material that would be inconceivable or illogical to deliver utilizing more routine biotechnological approaches. For instance, utilizing manufacturedgenomics it is conceivable to outline and amass chromosomes, qualities and quality pathways, and even entire genomes

  • Track 7-1Computational Genomics
  • Track 7-2Synthetic gene pathways
  • Track 7-3Regenomics
  • Track 7-4BioBrick
  • Track 7-5Functional genomics
  • Track 7-6Cheminformatics and Immunomics
  • Track 7-7BioBrick

Plan and development of Synthetic gene network from secluded segments is a noteworthy objective of engineered science. Nonetheless, the development of quality systems with unsurprising capacities remains hampered by an absence of suitable segments and the way that amassed arranges regularly require broad, iterative retrofitting to function as proposed. Propels in the improvement of atomic devices for the inducible control of interpretation, interpretation, and protein debasement are the premise for the quickly developing configuration and development of engineered quality systems in mammalian cells. Nonetheless, progresses in manufactured science have been constrained by an absence of interoperable parts, strategies for powerfully testing organic frameworks and systems for the solid development and operation of mind boggling, higher-request systems. As these difficulties are tended to, manufactured scholars will have the capacity to develop helpful cutting edge engineered quality systems with certifiable applications in prescription, biotechnology, bioremediation and bioenergy. Artificial gene synthesis amalgamation is a strategy in Synthetic Biology that is utilized to make artificial genes in the research facilities.

  • Track 8-1Genetic network analysis
  • Track 8-2Genetic network modeling
  • Track 8-3Gene transcription
  • Track 8-4Gene translation
  • Track 8-5Design and construction of synthetic gene networks
  • Track 8-6Mathematical modeling of cellular systems
  • Track 9-1Drug discovery and disease modeling
  • Track 9-2Cell growth and metabolite production
  • Track 9-3Biomedicine modeling
  • Track 9-4Constructing gene regulatory network
  • Track 9-5Structure of the network systems
  • Track 9-6DNA microarray technologies

Cancer systems biology encompasses the application of systems biology approaches to cancer research, in order to study the disease as a complex adaptive system with emerging properties at multiple biological scales.

Cancer systems biology therefore adopts a holistic view of cancer aimed at integrating its many biological scales, including genetics, signaling networks, epigenetics, cellular behavior, histology, (pre)clinical manifestations and epidemiology. The systems biology approach relies heavily on the successes of decades of reductionism, which has clarified the component parts and mechanistic principles of living organisms, as well as their key alterations in cancer, especially at the genetic/genomic scale, to deep detail.

  • Track 10-1Stem cell engineering
  • Track 10-2Single cell Imaging
  • Track 10-3Epigenetics
  • Track 10-4Epigenetics
  • Track 10-5Integrative Cancer Biology and Genomics
  • Track 10-6Cell Proliferation
  • Track 10-7Chromosome Biology

Biomedical Device Engineering includes instrumentation for diagnosing, preventing or treating diseases. The study and design of engineering methods without any chemical action in the body can be achieved through the Medical imaging devices.  Photo detectors and Biomedical Chromatography are recently obtaining their importance in the science field through its advancements.

  • Track 11-1Synthetic DNA and Synthetic RNA
  • Track 11-2Synthetic Protein
  • Track 11-3Artificial Organs and Tissues
  • Track 11-4Biomedical Chromatography
  • Track 11-5Synthetic Circuits
  • Track 11-6Synthetic Biology Drugs
  • Track 11-7Synthetic Biology Drugs
  • Track 11-8Advanced DNA Sequencing
  • Track 11-9Synthetic Enzymes
  • Track 11-10Synthetic Protein
  • Track 11-11Biomaterials (or) Synthetic Materials
  • Track 11-12Synthetic Protein
  • Track 11-13Advance Methods in Molecular Biology

Bioengineering is the manipulation of the biological compounds varying their physical and chemical forms using engineering principles and techniques. Engineering is done at cellular and subcellular level i.e. molecular level. Bioengineering is the “biological or medical application of engineering principles or engineering equipment. Recently, the practice of bioengineering has expanded beyond large-scale efforts like prosthetics and hospital equipment to include engineering at the molecular and cellular level  with applications in energy and the environment as well as healthcare.

  • Track 12-1Stem Cell Engineering
  • Track 12-2Bioprocessing Engineering
  • Track 12-3Single cell Imaging
  • Track 12-4Cell Culture

Synthetic biotechnology involves the manipulation of biological compounds like integration of synthetic aminoacids into proteins, DNA synthesis and manipulation using synthetic sequences, oligonucleotide synthesis, protein modification using synthetic compounds etc. the compounds produced synthetically are orthogonally integrated into cells which are chosen to provide suitable experimental strategy.

Synthetic biology represents a convergence of advances in chemistry, biology, computer science, and engineering. systematic methods for increasing the speed, scale, and precision with which we engineer biological systems. In a sense, synthetic biology can be thought of as the development of a biology-based “toolkit” that enables improved products across many industries, including medicine, energy and the environment.The manipulations in the wild type system by the engineered systems are studied varying their efficiency

  • Track 13-1Biotechnology and Biomaterials
  • Track 13-2Bioprocessing and Biotechniques
  • Track 13-3Chemical Engineering and Chemical Sciences
  • Track 13-4Nanomedicine, Artifiicial Cells and Biochemical Engineering
  • Track 13-5Biochemistry and Synthetic Biotechnology

Protein engineering is the procedure of creating helpful or profitable proteins. It is a youthful control, with much research occurring into the comprehension of protein folding and acknowledgment for  protein design principles. There are two general systems for protein engineering, rational protein design and directed evolution. These systems are not fundamentally unrelated; specialists will frequently apply both. Later on, more itemized learning of protein structure and capacity, and also headways in high-throughput innovation, might incredibly grow the abilities of protein engineering. In the long run, even unnatural amino acids might be incorporated, because of another strategy that permits the consideration of novel amino acids in the genetic code.

  • Track 14-1Plant genome editing (CRISPR systems)
  • Track 14-2Rational Design and mining of natural systems for plant synthetic biology components
  • Track 14-3Plastid Engineering artificial photosynthesis, metabolites and nitrogen fixation
  • Track 14-4Sustainable Environmental Systems and Photosynthetic Improvements

The pharmaceutical biology is a gathering of interdisciplinary zones of study concerned with the desigin, activity, delivery, and disposition of drugs. Applying the  knowledge from chemistry such as inorganic, physical, biochemical and analytical from one end and from another end of Biology is dealing with life structures, physiology, organic chemistry, cell science, and molecular biology, epidemiology, statistics, chemometrics, mathematics, physics, and chemical engineering. As new disclosures progress and amplify the pharmaceutical biology, subspecialties keep on being added to this list. These shared fundamental concepts further to the understanding of their applicability to all aspects of pharmaceutical research and drug therapy

  • Track 15-1Pharmaceutical chemistry
  • Track 15-2Pharmaceutical chemistry
  • Track 15-3Pharmacogenomics
  • Track 15-4Pharmaceutics
  • Track 15-5Pharmacodynamics
  • Track 15-6Pharmacology
  • Track 15-7Pharmacokinetics
  • Track 15-8Pharmacognosy

Structural biology is the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their function. Structural biology incorporates the principles of molecular biology, biochemistry and biophysics. Molecular Biology is the field of biology that studies the composition, structure and interactions of cellular molecules – such as nucleic acids and proteins that carry out the biological processes essential for the cells functions and maintenance.

  • Track 16-1DNA Damage and Repair
  • Track 16-2Cell division
  • Track 16-3DNA Recombination and Non-coding RNAs
  • Track 16-4DNA and RNA metabolism
  • Track 16-5Non-coding RNAs and Protein folding
  • Track 16-6Molecular Modelling

Genetic engineering refers to those techniques used to modify the genotype of an organism to change its phenotype. That is, genetic engineering manipulates an organism's genes to make it look or act differently. DNA technology refers to the methods used to modify, measure, manipulate and manufacture within the DNA molecule. Because genes are stored in DNA, genetic engineering is done with DNA technology. But DNA technology can be used for more than genetic engineering. With genetic engineering, scientists attempt to manipulate the genetic structure of an organism to make a change in the way an organism looks or functions.

  • Track 17-1Genetic Testing and Molecular Biomarkers
  • Track 17-2DNA Sequencing Machines
  • Track 17-3Gene Editing Technology
  • Track 17-4CRISPR/Cas9 Technology
  • Track 17-5Human Genome Project Updates

Transcriptomic profiling techniques include DNA microarray, cDNA amplified fragment length polymorphism (cDNA-AFLP), expressed sequence tag (EST) sequencing, serial analysis of gene expression (SAGE), massive parallel signature sequencing (MPSS), RNA-seq etc. The most recent technology for transcriptomic profiling is RNA-Seq which is considered as a revolutionary tool for this purpose. Eukaryotic transcriptomic profiles are primarily analyzed with this technique and it has been already applied for transcriptomic analysis of several organisms including Saccharomyces cerevisiae, Schizosaccharomyces pombe, Arabidopsis thaliana, mouse and human cell.

  • Track 18-1Single cell transcriptomics
  • Track 18-2Transcriptome analysis & gene expression
  • Track 18-3Transcriptomics & proteomics in microorganisms
  • Track 18-4Epigenetics

Next-generation sequencing alludes to non-Sanger-based high-throughput DNA sequencing technologies. Millions or billions of DNA strands can be sequenced in parallel, yielding considerably more throughput and minimizing the requirement for the fragment cloning techniques that are frequently utilized as a part of Sanger sequencing of genomes. DNA sequencing industry is sectioned into instruments and consumables, administrations, and workflow products.

  • Track 19-1Identification, expansion and testing of the BAC clone
  • Track 19-2Mathematical modeling of cellular systems
  • Track 19-3Modeling and optimization
  • Track 19-4Computational Genomics

A biosensor is an analytical device, used for the detection of an analyte,that combines a biological component with a physicochemical detector. Electrochemical biosensors are normally based on enzymatic catalysis of a reaction that produces or consumes electrons (such enzymes are rightly called redox enzymes). The sensor substrate usually contains three electrodes; a reference electrode, a working electrode and a counter electrode. Amperometric biosensors function by the production of a current when a potential is applied between two electrodes. They generally have response times, dynamic ranges and sensitivities similar to the potentiometric biosensors. The potentiometric biosensor, (potential produced at zero current) gives a logarithmic response with a high dynamic range. Such biosensors are often made by screen printing the electrode patterns on a plastic substrate, coated with a conducting polymer and then some protein (enzyme or antibody) is attached. They have only two electrodes and are extremely sensitive and robust. A microbial biosensor is an analytical device which integrates microorganism(s) with a physical transducer to generate a measurable signal proportional to the concentration of analytes.

  • Track 20-1Electrochemical Biosensors
  • Track 20-2Amperometric Biosensors
  • Track 20-3Enzymatic Biosensors
  • Track 20-4Microbial Biosensors
  • Track 20-5Potentiometric Biosensors

Stem cells will be cells begin in all multi-cell organisms. They were detached in mice in 1981 and in people in 1998. In people there are a few sorts of stem cells, each with variable levels of strength. Stem cell treatments are a sort of therapy that brings new cells into grown-up bodies for conceivable treatment of cancer, diabetes, neurological disorders and other medical conditions. Stem cells have been utilized to repair tissue damaged by infection or age. In a creating embryo, stem cells can separate into all the specific cells ectoderm, endoderm and mesoderm, additionally keep up the ordinary turnover of regenerative organs, for example, blood, skin, or intestinal tissue.

  • Track 21-1Synthetic Biochemistry
  • Track 21-2Synthetic organic chemistry
  • Track 21-3Green chemistry
  • Track 21-4Industrial production of Mobilized and Immobilized enzymes
  • Track 21-5Industrial Waste management