Stem Cell and Tissue Engineering

Natural cell phenotypes in tissues and organs are the result of stem cell differentiation at the embryonic stage of development. Although in vivo many natural biochemical/molecular biological determinants that instruct the direction of stem cell differentiation are well known (6, 7), very many cell types are also subject to native mechanical forces which also play a role in their phenotypic outcome. The source of stem cells may be either embryonic or adult (umbilical cord blood stem cells are generally classified as ‘adult’ though clearly a more appropriate term is sought). They should be either pluripotent, able to differentiate into cell types characteristic of any of the three developmental germ layers, or at least multipotent, capable of differentiating into varieties of an individual cell lineage.

  • Identifying stem cells
  • Embryonic stem cells
  • Cord blood cells
  • Adult stem cells and epithelial stem cells

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